Validated Instrument · Kivipelto et al., 2006, Lancet Neurology

CAIDE dementia risk explorer.

The CAIDE score is a published, externally validated tool for estimating 20-year dementia risk from midlife cardiovascular and lifestyle factors. Adjust the fields below to see how each factor contributes to the total score.

Demographics

Age0 pts
3045 years80
Sex0 pts
Education0 pts

Cardiovascular & metabolic

Systolic blood pressure0 pts
mmHg
Body mass index (BMI)0 pts
kg/m²
Total cholesterol0 pts

Lifestyle

Physical activity0 pts
Optional: APOE ε4 genotype (extended score)
APOE ε4 carrier status0 pts
0 / 15

total CAIDE score

05791115
low estimated risk
Score0–56–78–910–1112–15
20-yr risk1.0%1.9%4.2%7.4%16.4%

Point breakdown

What this is. The CAIDE (Cardiovascular Risk Factors, Aging and Dementia) score is a published, peer-reviewed risk instrument developed from a 20-year longitudinal Finnish cohort study and externally replicated in several other populations. It was designed to estimate dementia risk from factors measured in midlife (roughly ages 40–65); its accuracy outside that age range, or in populations very different from the original cohort, has not been established to the same degree. The APOE ε4 extension uses point weights reported in a later replication study and is optional, since genotype is often unknown.

This is an educational tool, not a diagnostic or clinical instrument. It does not diagnose dementia or Alzheimer's disease, cannot account for your full individual medical history, and should never replace a conversation with a physician. If you have concerns about memory or cognitive health, please speak with a doctor.

Source: Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurology. 2006;5(9):735–741.